c_mitra
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The input bias current in the feedback resistor (and maybe also in its other resistor) causes a voltage shift in the output voltage if the opamp. Usually an opamp has an extremely low input bias current so the effect is very small.
If your circuit needs a 10M feedback resistor and you do not mind having a voltage shift of 0.1V (when the other resistor is capacitor-coupled to ground) then a bias current of 0.1V/10M= 10nA will do it.
In the case of a pH meter (electrometer), current flows through a glass electrode that is typically in the range of pA and use opams with bias currents in the fA range. The price? The electrode response takes 10s of seconds. Again, we use feedback resistors in 10M or higher this is a case of impedance matching (and the voltage does not need much amplification; it is in the range of 100mV).