How can calculate the Bandwidth of analog circuit?

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hcs2536

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analog bandwidth

I have block diagram from a system and I want to improve bandwidth of system. I know, I must be draw by Orcad or PSPICE and simulate by Matlab but I don't know how can do it. I also want to know which component is cut off my bandwidth in system which is consisted : Input structure "Op-Amp,V-I, MUX(Switch Array), Electrodes", then Output part "Electrodes, Buffer, DE-MUX(Crosspoint Swtich), differential Receiver Amplifiers, and OP-Amp(Lowpass filter).
 

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