Hi,
High side switching is required when your MOSFET is in high side configuration. This is when the drain is connected to +ve and load is taken through source to ground. As a result source has no direct connection to ground. Here when +ve is 200v, your VGS has to be 200+10 = 210V because source is not directly connected to ground, and when on has a potential of 200v.
Low side is where load is taken from drain and source is connected to ground. Here, VGS is always eg 10v as source is connected directly to ground.
In bridge circuits you need both high and low side switching.
Hope this helps.
Tahmid.