Sorry, I don't understand what you are trying to do. To me, ground means one net, and there is nothing like "multiple isolated grounds". ADS had exactly one global ground. Anything else is another net.
Each net can have one name in ADS. If multiple nets are isolated, they can have different names.
It might be just an issue with wording, that you call multiple nets "ground" and I call them differently. For simulation any net can serve as a common return connection for multiple stages.