Yes, if the final stage is a depletion mode MOSFET you'll see a short circuit (a low ohmic value) from D to S. This because in depletion mode devices the channel is already present when no electric field is applied. When the transistor is polarized, applying a negative voltage to gate the channel opens increasing the D to S resistance.
The enhancement mode MOSFET is exactly the opposite: the D to S channel normally doesn't exist and is formed when a Vgs voltage, higher than a given threshold is applied.
You can see the depletion mode as a normally closed switch and the enhancement mode as a normally open switch.