I do not understand what do you mean by"peak phase error at the first bit"? I am not very clear on your question but I think your concern is reflected signal at the output of PA. In fact, if there is any mismatching at the output of the PA, the PA will be the first victim (might lead to permanent device/chip damage). This problem can be minimized by adding an isolator after PA. As for VCO, to minimize the pulling effect, add attenuator (match to 50 ohm) as close as possible to the VCO output. For isolation, you can choose either adding buffer amplifier/isolator after attenuator to minimize the effect. My recent investigation shows that isolation of at least 30dB is necessary between the VCO to other circuit (i.e.mixer).