Systematic way to Bias amplifier

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ccw27

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Hi,

What is a good strategy to determine the right bias voltage so the amplifier remains in saturation? For the enhanced source follower attached, I had a hard time to set the bias point for M1 and M5 so that all transistors remain in saturation. Basically I would like to know a more systematic way rather than trial and error in cadence.

Thanks
 

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