Hi
@nahid99
From the drawing provided it seems like your startup circuit doesn't even work (just look at the order of currents, it is in nanoamperes).
One of the ways you can verify that is by setting the initial condition in Spectre to force your Vbiasp=0 and Vbiasn=VDD. Your circuit most likely will stay locked in this condition, because your startup is enabling MN3 hence shorting Vbiasp and Vbiasn which wouldn't force the transistors in beta multiplier to start conducting.
The purpose of the startup circuit is to let the currents flowing your circuit at the initial condition -> hence we need to design a circuit that in your case will pull down Vbiasp to 0 and Vbiasn to VDD and disconnect when the currents will start flowing.
I could recommend using some circuit like this (attached). The key point here is that the diode-connected device (N3 on the drawing) has to be quite small (and probably long) so that the P4 should give more current after the currents will start flowing and hence will disconnect the P3 from the main circuit.
Hopefully, that helps.