You used small signal s-parameter for mixer (S4P). You cannot do LSSP with small signal models.You have to either use large signal model of the mixer or you should build up this mixer with the same diodes with their large signal models.Otherwise you can not see anything...
OR.. (and this is only a crazy idea!) maybe as a start, he might try temporarily not attempting LSSP, and using the manufacturer provided model slightly modified, at least to explore the matching, and maybe get the lengths and widths right.
The diodes in mixers cannot reasonably live in a linear small-signal model, but he might perhaps mess with the model a little, and remove the "diode" part from the model, leaving only the parasitic capacitances, lead inductances, bulk resistance, etc.
Then - simulate in a normal way. Find out the best lengths and widths to give a good RLR at the ports. Simulating only sections of the network driven at a frequency which assumes the mixer had already successfully mixed might be a fast way to figure out most of the circuit. Using the manufacturer model, removing the diode, and replacing it with a RF source of low impedance. (Telling it lies!)
BigBoss is right in that you cannot do large signal simulation of things that contain non-linear stuff using only linear small-signal models. One thought that does occur is .. if there was a manufacturer-supplied model in the first place,
and it was of a mixer, this being a non-linear thing, then what kind S-parameter simulation setup did it ever use, even once, when the model was first thought up and tried?
Is the manufacturer-supplied "model", a sub-circuit type, or a sub-circuit with equation based blocks in it, or is it maybe a big table of S-Parameters?