From the direction the thread friendly chat is taking, re to simulate or not to simulate, I wasn't saying simulators are no use, that would be silly. Every tool has its place when making something.
I imagine as the years go by it will become impossible to breadboard as the parts will be so small and BGA etc. that the only method will be simulation, or being Einstein with a calculator, which as one poster maybe sort of said - won't be the case for most of us.
Simulators are useful as they can show up a lot of things you may not see or think about, but they are also quite hard to use and get a meaningful result from if you don't set every single parameter individually or understand the virtues and limitations of a set of algorithms, which I certainly can't do, and as some-one else said: best laid plans of designers and then the reality shows up unexpected quirks.
Anyway, all tools have a place, and should make the job easier, as does the tool of real world analysis, but it's pointless saying one method is "better" than another as no toolkit is 1 screwdriver or 1 hammer.