Some additional comments.
-I think you would want to use the minimal available via size in your technology to achieve best RF performance, e.g. 10-12 mils drill.
-If you take a look at the Hittite demo design, you'll realize, that they have a continuous top layer ground under the chip, connecting to top copper pour on both sides, also directly connecting all IC ground pins. That's much better than having individual GND vias with rather long (high inductance) traces as in your design.
-If you need "fence" vias at all, than near the transmission line, as shown in the Hittite layout example.
-You'll get some impedance discontinuities and parasitic via inductances by using a rather thick substrate. But I think it's no problem at < 1 Ghz.
- I agree that designing a grounded coplanar rather than pure microstrip is better in this case. The Hittite example also does in my understanding.