Hello
Depends on what you're trying to power with it and how sensitive the load is to spikes and what not.
If it's a relatively simple load (motor, lightbulb/LED, etc.) then the simple answer is no.
If you're trying to make a power supply for (say) an audio amplifier, noise on the power line plays a big role in the output quality.
But in most cases, the noise can be filtered with LC circuits, so no real need in the whole transfer function shebang.
You need to know the zeros and poles for when your circuit might oscillate out of control and what not.
If you're using a microcontroller, just make sure your code changes PWM correctly, depending on the output voltage.
One more thing, if I were you, I wouldn't use a potentiometer, unless you want adjustable output voltage.
Use a precision voltage divider of a known ratio instead (do a quick digikey search)
They are not exactly cheap, but again, depending on your exact needs, may do the trick:
https://www.digikey.ca/product-detail/en/MPMT1003AT1/MPMT-50K/50KCT-ND/1771078
https://www.vishay.com/docs/60001/mpm.pdf
Just remember one thing, 4:1 ratio means measured voltage will be Vout*1/(1+4)=Vout/5=Vout*0.2
(or Vout*4/(1+4)=Vout*0.8, depending on your connection).
Hope this helps.