I need to use a PLL to generate a 25Mhz clock from reference clock 12KHz.
But I have no idea if the feedback divider values N has any limit. Is the values
(>2000) reasonable?
It is very reasonable, for example the GSM frequency synthesizer generates 900MHz from a reference frequency equal to 200KHz, i.e. the division ration is within the 4000 range
The only problem you may have is the phase noise: the loop transfer of function of most noise sources in PLL is proportional to N. But N=2000 is not high value.
To generate the 25MHz Frequency, why not try to use the pre-divider divide by 11,
and the loop-divider divide by 23?
By the way, the output frequency will be
12MHz X 23 /11 ≈25MHz