Yes, but when you want to measure the S-parameter be very careful to connect the network analyzer to the output of the amplifier: you risk to damage the instrument. Even if you input power is low, unless you are very very sure the amplifier is stable, an instability can generate an unwanted full power (10W or more) signal. I think you could use an attenuator (roughly 40 dB 20W) from the output of the amplifier to the port 2 of the NA, that you have to insert during the SOLT calibration. In this way you will loose the information about S22 (it will appears as perfectly matched) but the other three params will be valid.