we have three types of defects:-
1. Random defects - related to particle defects. mainly cause shorts and open.
2. Systemetic defects - induced due to process or lithography applications.
3. Parametric defects - when all the devices are working fine, but the specs like timing or power are not met.
for dimensions larger than 180nm, only random defects were important, but for dimensions less than 180nm all these have their contribution.
in your case you have to consider on the second point i.e. systemetic defects.
systemetic defects:-
Induced by process or lithography applications.
E.g. 1) Planarity.
2) Antenna effects.
3) Via opens (due to voids).
4) Electro migration.
5) RET issues – requires pitches.
- specific interactions on shapes between layers
foundaries provide some guideline rules to combat these systemetic errors.
these rules provide layout engineers with some layout styles, which when followed will reduce the percentage of systemetic defects........and hence improves yield.
E.g.
1) Poly end cap rules.
2) non minimum metal width and metal spacing.
3) Redundant vias, etc
these are included in the DFM rule deck, so you can check in the DRM provided by the foundary.........that will be the best place where you can find all these layout styles.
hope this helps you...........