Using a lower dielectric constant material will decrease the crosstalk for the same characteristic impedance. The dielectric constant, also known as the relative permittivity, is a measure of a material's ability to store electrical energy in an electric field. A lower dielectric constant means that the material can store less electrical energy and thus reduce crosstalk.
In high-speed PCB designs, it is important to use materials with lower dielectric constants to minimize crosstalk, reduce signal distortion, and maintain signal integrity. For example, in designs with high-speed serial interfaces such as USB, HDMI, or PCIe, using a lower dielectric constant material can help improve the signal quality and reduce bit errors. It can also be important in designs with multiple high-speed signals running close to each other, such as in a DDR memory interface or a high-speed backplane.