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I have done upto 125MSP\s using Analog device ADC and transferred into a host device (ARM controller) using Virtex-4 FPGA. Sampling was easier since it was a parallel high speed ADC, however for PC interface you might need PCI or PCIe interface. Using ethernet is another option, but it is good if you use PCIe, since it can be easily interfaced in backplane of the Mobo. Many dev boards do come with this interface.