Hi,
First: Why?
If you don´t have a good reason (and the knowledge what will happen), then simply don´t do it.
Impact:
On impedance mismatch you get echoes. It means the signal you send will be reflected. One "edge" sent will cause several additional edges on the wire/trace. Depending on the magnitude of the echoes the data may become currupt ... up to complete imposssibility of reliable data transfer.
50 Ohms transmitter --> 50 Ohm PCB traces --> 50 Ohms cables --> 50 Ohms termination.
Mind: This is characteristic impedance (cable, traces) and can´t be measured with an ohmmeter.
Klaus