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Thanks you very much, i will keep updated with my result... I hope I will be able to do some measurement using my little nanoVNA...

I think I will try firstly to get a single ended with 50ohm terminated single port S parameter and try to compare my result with HFSS.

Secondly, I will try to measure differential response single port with 2x50 ohms ended as my nanoVNA seems  to have two ports. I will also need to deembed the SMA connector/cable before the molex.

For my project, I want to transmit VDSL data using 24inches of this molex cable, SPI speed at about 15Mhz with rise/fall time not lower than 15ns so I think it should be ok... But I would like to test it under HFSS/Circuit...

It's a personnal project so I dont care too much about EMI, only about SI...