how to use opto
Still you have to preprocess input signal with amp before driving it into an optocoupler. It means, you have to isolate power supply for powering an amp. And also you have to deal with optocoupler non-linearity (in analog circuit)
By my opinion, it's better to isolate at 2 places (in digital circuit and power supply) instead of isolating every input.
Moreover, if you look at the 12V adapter, you will surely notice, that it's very cheap smps with very basic surge voltage protection (sometimes even without it).