Can you give an idea about the range of observed differences?
Regarding the difference between simulations, a simple explanation would be that the Simulink IGBT model behaviour differs from datasheet specification. You can further differentiate the simulation results to see where it is.
Regarding real hardware behaviour, differences are likely to observe. You would need to measure IGBT current and voltage waveforms during switching, calculate on-state and switching loss energies and try to locate the differences.