Guitar amplifiers use a 1/4" mono jack input. This means that one side of the signal is earthed, unlike proper PA/studio equipment which uses a balanced signal to break the earth path and so reduce the chances of hum loops. The only way to truly break hum loops is to use transformers.
The magnetic pick ups for guitars only produce 10 mV or so, so the amplifiers are very sensitive. most microphones will produce more then this, other then the moving ribbon type which is a very expensive studio type , these produce 1mV.
The input impedance of a guitar amp would normally be about 10K.
So driving the input of a guitar amp is easy, the only area up for discussion is the cable capacitance, so the pre-amp should have a low output impedance to deal with long cables.
Words of wisdom?, think about anti thump circuits, so switching on the pre-amp does not cause a 100Watt thump in the loudspeakers of the main amplifier.
Frank