First, the leakages on a circuit (a printed circuit board) are very small. not milliamps, but much smaller. The guarding usually may be required only, when the current levels are below microamps. That is an answer to your last question: When guarding might be necessary: When the input signal currents are very low. There is no "hard limit" as depending on application, environment, and other circumstances, value of "low" can vary quite much. On printed circuit boards we talk usually about nanoamperes or at most microamperes. On some other cases, fractions of picoamperes. Or in the other extreme, we might have many tens of microamperes or even more - but rarely.
The reasoning for guarding is quite straight forward:
You may have heard about Ohms law. That law defines the equation for leakage currents, (as well as for any other currents) as function of voltage and resistance (or impedance, if we consider AC and reactive components as well).
Let's keep it simple, and the leakage is just a resistance, value R.
The voltage between the sensitive input node and "something else" on other side of the leakage, has a voltage U, relative to the input we are observing.
Then the leakage current "I" would be = U/R. It is then obvious, that if the value of R (the leakage resistance) is constant, the current would be reduced easily by reducing voltage U.
The guard, by tracking closely the input voltage, would keep the voltage U very low, thus reducing the leakage current.
I don't understand how a guard plane can lower the leakage current because it will be at the same voltage potential
if the leakage current is in the milliamps, a guard plane can lower the leakage current to picoamps, how so?
How do you know when your circuit or stage in a circuit needs a guard plane?
What are some common signs of when a circuit or stage needs a guard plane?