Looking at the first design, Optimization_L_C_R, there are many items entered incorrectly and a couple of these are blocking the simulation from working.
In the second design, Optimization_L_C_R_Modi, you appear to have 'fixed' most of these issues but there is still one remaining. In the Optimization Goal OptimGoal1 you have the Swept Variable set as both "Freq" and "freq". ADS does not know what "Freq" is (ADS is case sensitive). Delete the "Freq" value and leave only the "freq" setting. The Optimization should now run.