Drain of NLDMOS as shown, does not want to be tied to a power
net. So doing would ruin anything but a source follower.
The HV PMOS will need to sit in a HV NWell and that wants a N+ ring.
The layout appears to have concentric guardrings. You might have to
connect them individually to opposing rails, according to "hidden"
net connection properties. I recommend you find proper cross sections
so you can understand the isolation scheme, which can be complex and
"fussy" when you have to deal with junction isolation on flying high
voltages (and faults).