Well.......... (pause for comedic effect)
Perhaps a use for such isolation is to provide for higher voltage devices. I know that where I work we have some processes which have fancy isolation schemes for high voltage, although I don't know if they would be termed a "triple well process". For example, they etch a (microscopic) huge trench into the silicon to create an electrically isolated pocket.
Yes, I am working with double and triple trench design in high voltage. The bulk (spacing) between the trenches themselves can also reach high voltages so it's best not to route wires over them.