Funny I just put this on your other post -
Re: Circuit debugging help please.
From past experience with analog switches, similar to what you are using, two things come to mind -
1. Ron (the on resistance) of these switches can changes drastically with supply voltage. Doubling in value from the manufacturers published headline value as the supply voltage is reduced is not unusual.
2. Analog switches are touchy about power supply sequencing. To quote from Analog Device on this topic -
"Care must be taken to ensure correct power-supply sequencing.
Incorrect power-supply sequencing can result in the device being subjected to stresses
beyond those listed in the Absolute Maximum Ratings. Always sequence VDD on first
followed by VSS and the logic signals. An external, analog or digital, signal can then be
safely presented to the source or drain of the switch."
****************Other manufacturers have similar statements.***************
I would advise a good look at the switch manufacturers datasheet if you haven't already done so.
And good luck.