Converting an ADC value to Equivalent Process value?

I'm working on a humidity controller which also controls the temperature inside a chamber.I'm done with the hardware (though i'm not the one behind the design)and which was originally designed with a 12 bit external ADC and an 89s52 uc and I replaced both with PIC 16F877A uc and I use the 10 bit internal ADC.

Other hardware details are (I can provide the schematic though it seems cumbersome).
View attachment khc_schem.JPG
temperature sensor -PT100
humidity sensor - SY-HS-220 (datasheet)
+Vref for ADC - 1.235V and -vref =0;
I roughly checked the voltage across the 2 ADC channels by replacing the sensors with a 500 ohm pot (not concerned about the errors at this point) and got the following figures

proposed temp | voltage @ ADC

5 oC--------------------1.650v
6 oC--------------------1.660v
80 oC------------------2.480v

proposed humidity | voltage @ ADC

30% (990mV)--------0.098V
31% (1023mV)-------0.101V
32% (1056mV)-------0.104V
33% (1089mV)-------0.107V
34% (1122mV)-------0.110V
40% (1300mV)-------0.128V
90% (2970mV)-------0.29V

I want to use this hardware for the following requirements

Temp. measurement - 5-80 oC, 0.5 oC resolution
Relative Humidity - 30-90%, 1% resolution

And my concerns are


1. Should I have to change the reference voltage to 2.5V as I can see the maximum voltage to be measured is 2.48? Or that voltage is out of a mistake since the original hardware is designed with 1.235V

• is the voltage at the ADC in(of temp sensor) adjustable so as to make it within 1.235V (so I think better performance) by some minor hardware changes (like changing a resistance value to change gain of amp)
  are my requirements achievable with a single ADC configuration as I'm concerned about the rough figures I got (ADC input values for temp and humidity are not comparable or that too a mistake?) ?

2. for the temperature I could measure only with 1 oC in steps as the RTD chart (For European **broken link removed**Curve, Alpha = .00385, ITS-90)was provided with 1 oC increments. To measure 0.5 oC resolution is it OK if I divide the change in voltage for 1 oC increment by 2 (assuming the curve is linear, or not!?)

3.How to decide efficiently the sampling time of ADC (considering the facts that the sensors respond slowly, transient voltage fluctuations in the line etc.)

4. Finally how ADC values are converted to equivalent process values.? (Excuse me if the title of question matches here only)

• By a table look up? (in my case 150 values(for temp) + 60 values(Rel humidity) ) or can I use some calculation ? (if yes, how to get a linear relationship between the ADC values and process values) .which method is efficient in terms of accuracy?