hi,
It mostly deends on many enviromental factors - how noisy your enviroment is, driver rise/fall time causing reflections on unterminated (if) lines, the data transfer speed etc. The differential protocols (RS422/485) are intended to eliminate common-mode noise from enarby sources.
Thus, if encounter problems, you should try:
1) series termination resistors, plased near driver's output - does make sense on UNIDIRECTIONAL lines. Something about 50 ohm value.
2) Decreasing the speed of data transfer
3) May be, consider additional shielding of communication cabling