* It looks as though your reference voltage is the same as overall supply voltage. Reference voltage should be your desired load voltage.
* To properly turn off the Pmos, your IC needs to send 3.3V, referenced to the Pmos source (more positive) terminal. This means your IC needs to receive its power from the supply labelled V0.
* To properly turn on the Pmos, your IC needs to be grounded to the same ground as V0. One is connected to 'gnd', the other is connected to 'gnd1'. Are these exactly the same ground?