Each company has its own set of scripts and tricks for parasitics debugging.
You can follow them, or you can use commercial tool to do that for you.
Our company, Diakopto Inc., developed an EDA tool, ParagonX, specifically to help debug parasitics problems, you can read more here:
I recently read John Cooley’s interesting article on the Troublemakers panel discussion at DAC 2020 between Mentor’s Joe Sawicki and Cadence’s Anirudh Devgan. They were talking about Mentor’s AFS-XT SPICE simulator beating Cadence’s Spectre-X in speed by a factor of 3x-10x.
ParagonX lets IC design engineers shift left to quickly explore and find the root causes of parasitic-induced design issues.