At that kind of pulse width you're well within the
switching regime of GaN FETs (seen designs down
to ~ 10ns FWHM) and timer ICs. It'd be cheap and
easy to build a 74AC123, 74AC04, EPC or GaN
Systems FET (depending on what kind of packaging
you like to work with) and figure out your isolation
(presuming you want a positive HV rail, and a ground
referred trigger).
You could use a single lithium cell for the gate drive
and a pulse xfmr for the '123 trigger perhaps, or a
fast opto, or a more modern isolator if you like
depending on what you might expect or desire for
common mode dV/dt.