The first one is a RF Power Amplifier, the second one is a Transmitter Circuit.
They can work or not coupled together, nobody may say something without analyzing these circuits for the time being.I suggest you to realize the PA first and test it very well and ensure that the PA works well in your specifications, then realize the second one.
Because if you obtain a good response from the PA, second one will be easier.
But -as you said- if you're new to RF, I recommend you to read some related textbooks and application notes about RF, especially RF Power Amplifiers because RF is not like AF. RF Power Amplifiers particularly need very strong experiences and measurement techniques so it's really tough.
You have to find a appropriate Spectrum Analyzer, RF Power Meter, High Watt Attenuators,Signal Generator, proper cables etc. You have a long road to walk.
And don't forget to arrange a Transmitter Antenna.