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Closest to this problem I have used the normal-incidence method to determine the complex permittivity of concrete at ~50 GHz.
Details can be found in olivka, J,: Measuring Concrete Permittivity at MM waves, Internat. Journal of IR and MM Waves, Vol.17, No. 10, 1997, pp. 1673-1683.
From S11 you can derive the standing-wave ratio ; for a full reflection, SWR o, for a particular-material boundary reflection, SWRx. Then the reflection ratio gamma, G = ( SWRo-1)(SWRx+1) / (SWRo+1) (SWRx-1).
Then the complex permittivity k = k' - j k" = [ (G +1) / (G+1)] squared.
I have not thought about using S11 directly as it would involve the transducer parameters between your transmission line and a tested material.
Please let me know your results, it may be quite interesting. Thank you